Delta employees at airports throughout the mid-Atlantic, Northeast and New England are preparing for a strong Nor’easter, the first major storm of 2018, expected to produce high winds, bitterly cold temperature several inches of snow accumulation. Boston could see as much as 15 inches at the airport.

In anticipation of the severe winter weather, Delta will proactively cancel more than 400 mainline and Delta Connection regional flights Wednesday evening and Thursday, primarily at New York JFK International and LaGuardia airports as well as Boston’s Logan International.

As for now, Delta has suspended operations at the Savannah/Hilton Head International Airport and Brunswick Golden Isles Airport in Georgia Wednesday due to severe weather—resulting in snow and ice accumulation on runways and taxiways—from a powerful Nor’easter making its way north along the eastern seaboard. Operations are tentatively expected to restart midday Thursday after a facilities assessment.

Additional cancellations are possible. These are expected at coastal airports in the storm’s path across the mid-Atlantic, New York area and New England region.

In order to facilitate an efficient restart to the operation once the storm passes, Delta will reposition some aircraft away from the New York and Boston airports so they can be flown in as soon as conditions improve and runways are cleared of snow.

Customers are encouraged to visit Delta.com or the Fly Delta Mobile App to check the status of their flight before arriving at the airport. The airline Tuesday issued a winter weather advisory for much of the east coast stretching from north Florida to Maine, allowing customers with flexible travel plans to adjust their itineraries around the winter storm without incurring a change fee.

Delta has so far canceled 45 mainline and Delta Connection flights as a result of the storm.